INTRANASAL DELIVERY OF A CHIMPANZEE ADENOVIRUS VECTOR EXPRESSING A PRE-FUSION SPIKE (BV-ADCOV-1) PROTECTS GOLDEN SYRIAN HAMSTERS AGAINST SARS-COV-2 INFECTION

We evaluated the immunogenicity and protective ability of Bookmark a chimpanzee replication-deficient adenovirus vectored COVID-19 vaccine (BV-AdCoV-1) expressing a stabilized pre-fusion SARS-CoV-2 spike glycoprotein in golden Syrian hamsters.Intranasal administration of BV-AdCoV-1 elicited strong humoral and cellular immunity in the animals.Furthe

In the current global context, where drinking water sources are constantly diminishing, surface water pollution has become an environmental problem that requires rapid action to conserve drinking water sources and protect aquatic biodiversity.Water pollution has many causes and can be caused by nitrates, detergents, pesticides, heavy metals, petrol

Research on power line extraction technology using mobile laser point clouds has important practical significance on railway power lines patrol work.In this paper, we presents a new method for automatic extracting railway power line from MLS (Mobile Laser Scanning) data.Firstly, according to the spatial structure characteristics of power-line and t

This scientific paper deals with religious Orthodox holidays and their significance within Serbian culture.The facts that celebration of religious holidays Seating has been very widespread in recent years and that they have been receiving extensive media coverage are indicative of their considerable social importance and topicality.Religious holida

The article deals with one of the striking features of the archaeozoological material from the Bronze Age sites in the Southern Urals, which is HAWTHORN expressed in the longitudinal fragmentation of livestock bones.Analysis of archaeozoological collections shows that this feature of bone fragmentation covers all major periods of the Bronze Age and